What is Cryoglobulinemia?

Cryoglobulinemia meaning Clinical disease characterized by cryoglobulins in the serum; often associated with immune complex antigen-antibody deposits in the kidneys and other tissues. It is the presence of abnormal proteins in the blood, which thicken in cold temperatures.Three types of cryoglobulinemia have been described: Type I (monoclonal cryoglobulinemia) Type II (mixed cryoglobulinemia) was first noted in WM, and can be seen as well in auto-immune disorders Type III (mixed polyclonal-polyclonal cryoglobulinemia) can be seen with auto-immune diseases, infections, and other medical diseases.


reference: national Cancer Institute – Glossary for Registrars

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