What is Backbone?
Backbone meaning The two nucleoside reverse transcriptase inhibitors (NRTIs) upon which an initial HIV regimen is built. To complete the HIV regimen, the two NRTIs are combined with a third antiretroviral HIV drug from either the non-nucleoside reverse transcriptase inhibitor (NNRTI), protease inhibitor (PI), or integrase strand transfer inhibitor (INSTI) drug class. Related Term(s): Integrase Strand Transfer Inhibitor, Non-Nucleoside Reverse Transcriptase Inhibitor, Nucleoside Reverse Transcriptase Inhibitor, Protease Inhibitor, Treatment Regimen
reference: AIDSinfo – GlossaryWhat is