Cross Resistance

What is Cross Resistance?

Cross Resistance meaning Resistance to one or more drugs that occurs as a result of previous exposure to a similar drug. For example, HIV resistance to one non-nucleoside reverse transcriptase inhibitor (NNRTI) drug may produce resistance to all drugs in the NNRTI drug class, including drugs never used. Excluding all drugs in a drug class from an HIV regimen (drug sparing) is a strategy used to prevent cross resistance. Related Term(s): Class-Sparing Regimen, Drug Resistance


reference: AIDSinfo – Glossary

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