Mixed-Tropic HIV

What is Mixed-Tropic HIV?

Mixed-Tropic HIV meaning HIV that includes both CCR5-tropic and CXCR4-tropic virus. To enter a host CD4 cell, HIV must first attach to a CD4 receptor, then attach to either a CCR5 or CXCR4 coreceptor, and finally fuse its membrane with the CD4 cell membrane. Related Term(s): CCR5, CXCR4, R5-Tropic Virus, X4-Tropic Virus


reference: AIDSinfo – Glossary

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