c-ABL

What is c-ABL?

c-ABL meaning An enzyme that is involved in many cell processes, such as cell division. The gene for c-ABL is on chromosome 9. In most patients with chronic myelogenous leukemia (CML), the part of chromosome 9 with c-ABL has broken off and traded places with part of chromosome 22 to form the BCR-ABL fusion gene.

 

reference: national Cancer Institute – Glossary for Registrars

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